It is proven to be one of the most effective air cleaners on the market today and will likely clean your air of both solids and gases such as Toluene and Formaldehyde with the highest efficiency compared to other air purifiers. Adverse effects included reduced appetite, nightmares, vertical nystagmus, and incoordination. Lower level acute exposures in man produce dizziness, exhilaration and confusion. Schedule controlled behaviors have been reported to produce inverted U-shaped concentration-effect curves on response rate measures. In each incident the acidosis was resolved within 3 days of birth. Tokyo, Japan: The International Technical Information Institute, 1988., p. 526]**PEER REVIEWED** Probable Routes of Human Exposure: NIOSH (NOES Survey 1981-1983) has statistically estimated that 1,625,598 workers (288,299 of these are female) are potentially exposed to were documented: manufacturing of metals, 420; manufacturing of metal fabricated products 64,000; electrical machinery and apparatus, 1,500; manufacture of transport equipment 2,700; painters and carpenters 15,000; construction workers, 5,400; publishing and printing, 6,300; wholesale trades, 5,000; textile and leather manufacturing, 4,400; wood and furniture manufacturing, 5,900; manufacture of chemicals, 8,700; manufacture of paints and petroleum, 1,400; manufacture of non-metallic mineral products, 2,300; manufacture of optical instruments, 2,500 manufacture of plastic and boat building, 1,100; sewage and refuse disposal, 99; agriculture and forestry, 11,000; health services, 2,600. Use proparacaine hydrochloride to assist eye irrigation ... /Aromatics hydrocarbons and related compounds/ [Bronstein, A. FOUR TIMES THERAPEUTIC DOSE RATE PRODUCED NO OBSERVABLE CHANGES IN ... Each point on the frequency versus time plot were further analysed by Student's t-test. IQ Air GC Chemisorber contains an impressive 12 pounds of the advanced Carbon-Potassium Permanganate filter media and has a very sophisticated gas filtration cartridge system plus highly efficient HEPA filtration for the removal of the tiniest of solid particulates as well. Alterations at levels as low as 150 ppm have been reported when appetitive contingencies are used. Pittsburgh, PA: Allied Fischer Scientific, 1985., p. [Lindemann R; Acta Pediatr Scand 80: 882-4 (1991) as cited in U. Dept Health & Human Services/Agency for Toxic Substances & Disease Registry; Toxicological Profile for Toluene (Update) p.49 (1994) ATSDR/TP-93/14]**PEER REVIEWED** Several case series have demonstrated that high exposure to through sniffing during pregnancy induces a syndrome that closely resembles the fetal alcohol syndrome, with pre- and postnatal growth deficiency, microcephaly and developmental delay, typical craniofacial features including micrognathia, small palpebral fissures, and ear anomalies. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man. 526]**PEER REVIEWED** The clinical examination should include hemocytometric testing and a thrombocyte (platelet) count in view of the possibility that may contain a certain proportion of benzene. The total number of work related exposure events was 140,000(3). 181-2]**PEER REVIEWED** Advanced treatment: Consider orotracheal or nasotracheal intubation for airway control in the patient who is unconscious or in respiratory arrest. Compared to the non-exposed group the eight hours daily exposed showed an initial period of increased frequency of the regular theta-waves together with an increased incidence of theta-activity after 1-2 weeks of exposure. These factors include the dose (how much), the duration (how long), the route or pathway by which you are exposed (breathing, eating, drinking, or skin contact), the other chemicals to which you are exposed, and your individual characteristics such as age, gender, nutritional status, family traits, life-style, and state of health. Autopsy was performed and neuropathological findings were as follows. This report is presented to invite comments from other researchers. Hazardous Materials Toxicology-Clinical Principles of Environmental Health. 1090]**PEER REVIEWED** Children with microcephaly, minor craniofacial and limb anomalies, central nervous system defects, attention disorders, developmental delay, learning disorders, and language deficits were born to mothers who abuse by inhalation during pregnancy. The granule cell layer of animals exposed to 100 ppm appeared qualitatively normal. Hatchability of the eggs was 85%, 25%, and 0 with exposures of 4.3, 8.7, and 17.4 mg/egg, respectively. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man. Hazardous Materials Toxicology-Clinical Principles of Environmental Health. 1092]**PEER REVIEWED** The cardiovascular response of 25 mongrel dogs following exposure to 30,000 ppm for 9-10 min was complex. is not classifiable as to its carcinogenicity to humans (Group 3). Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man. 1) Diffuse demyelination and gliosis of the cerebral and cerebella white matter. [Sakata E et al; Pract Otal Kyoto 79 (12): 1999-2013 (1986)]**PEER REVIEWED** Severe, acute in man and to the choice of reference parameters to monitor intoxication. 166]**PEER REVIEWED** Eye and upper airway irritation occurred after a 6.5 hr exposure to an air level of 100 ppm (377 mg/cu m) , and lachrymation was seen at 500 mg/cu m. Monographs on the Evaluation of the Carcinogenic Risk of Chemicals to Man. The alterations reported here support the few earlier reports of morphological alterations in the CNS of adult laboratory animals. Geneva: World Health Organization, International Agency for Research on Cancer, 1972-PRESENT. V47 96 (1989)]**PEER REVIEWED** was reported to induce chromosomal aberrations in the bone marrow cells of male albino rats after chronic inhalation exposure to 5.4 or 50.7 mg/cu m on 4 hr/day, five days/wk for four months or after sc injection of 0.8 g/kg bw. For most of the animals, there was no change in electrocardiogram readings for the first 3-4 min of exposure. Since tiny gas molecules such as Toluene and Formaldehyde will pass right through HEPA filters, air cleaners for Toluene removal must contain advanced gas filters besides just efficient air purifier HEPA filters which catch the tiniest of particulates, but not gases. 1455]**PEER REVIEWED** A report of 2 children who sniffed glue containing . He also developed bilateral optic atrophy with blindness and severe sensorineural hearing loss. When the exposed subjects were divided into two groups, one with TWA exposures of less than 40 ppm and the other with exposures greater than or equal to 40 ppm, the incidence of headache and sore throat, but not dizziness, showed a dose-response pattern. Geneva, Switzerland: International Labour Office, 1983., p. 870]**PEER REVIEWED** Populations at Special Risk: Preclude individuals from exposure to who have central nervous system or liver diseases. Toxic and Hazardous Industrial Chemicals Safety Manual. did not produce positive results in the majority of genotoxic assays. Threshold Limit Values for Chemical Substances and Physical Agents and Biological Exposure Indices. 56]**PEER REVIEWED** Non-Human Toxicity Excerpts: A TEMPORARY INCOORDINATION WITH MUSCULAR TREMORS HAS BEEN OBSERVED IN PUPPIES & KITTENS & IN DOGS AT TWICE THERAPEUTIC DOSE LEVEL. The hippocampal electric activity was recorded 48 hours after each weekly exposure. Sax's Dangerous Properties of Industrial Materials. The major issues addressed by the advisory team were the need for additional salvage equipment and expertise, the danger of toxic fumes from the fire and explosions aboard the ship, the presence and possible release of tetraethyl lead, possible port blockage by the wreck, recovery of the chemical drums, and the extent of environmental damage caused by the release of oil, pesticides, and tetraethyl lead into the harbor. [Heare SF et al; 1986 Hazard Matl Spill Conf p.12-18 (1986)]**PEER REVIEWED** Immediately Dangerous to Life or Health: 500 ppm [NIOSH. With this in mind, the best of breed air purifier for Toluene removal from indoor air is IQAir GC Chemisorber Multigas or VOC. One of the children became comatose after an episode of "sniffing" which lasted for several hours. [Ehyai A, Freemon FR; J Neural Neurosurg Psychiatry 46 (4): 349-51 (1983)]**PEER REVIEWED** exposures produced incoordination, ataxia, unconsciousness and eventually, death. [Yin S et al; Ind Health 25: 113-30 (1987) as cited in U. Dept Health & Human Services/Agency for Toxic Substances & Disease Registry; Toxicological Profile for Toluene (Update) p.41 (1994) ATSDR/TP-93/14]**PEER REVIEWED** Children born to abusers have exhibited renal tubular acidosis immediately after birth due to hyperchloremia. 3190]**PEER REVIEWED** Medical Surveillance: Yearly physical examinations of exposed personnel, with special attention to the eyes and central nervous system, including complete blood count and liver function tests. Toxic and Hazardous Industrial Chemicals Safety Manual. 2185]**PEER REVIEWED** Hippuric acid levels above 5 g/l of urine may result from exposure greater than 200 ppm determined as a time weighted average. Handbook of Toxic and Hazardous Chemicals and Carcinogens, 1985. Tokyo, Japan: The International Technical Information Institute, 1988., p. Currance; Emergency Care for Hazardous Materials Exposure. CALVES IN POOR CONDITION SHOWED STAGGERING GAIT AND SOME COLLAPSED BUT RECOVERY WAS COMPLETE AFTER UP TO 4 HOURS. Frequencies of theta-activity in the exposed groups were found to differ from their respective control group by variance analysis. 3190]**PEER REVIEWED** Hazardous Decomposition: When heated to decomposition it emits acrid smoke and irritating fumes.
[Boewer C et al; Int Arch Occup Environ Health 60 (3): 181-6 (1988)]**PEER REVIEWED** General health effects include lethality, growth, morbidity, liver and kidney damage and miscellaneous effects. influences neurological response after exposure to to a lesser extent than older rats (120 days old) based on several measurements of escape latency 30 days after exposure to 30,000-40,000 ppm for 15 min/day. All urine was collected and analyzed for radioactive content until background levels of activity were approached. [ANGERER J; INT ARCH OCCUP ENVIRON HEALTH 43 (1): 63 (1979)]**PEER REVIEWED** In rats, approx 0.5%-1.1% of the dose is converted to o-cresol and p-cresol and is excreted as glucuronide and sulfate conjugates.
The differential diagnostic examination showed in 51 of these 55 subjects an association with competing factors such as alcohol abuse (78%) and overweight (40%), to a slight extent disorders of fat and carbohydrate metabolism and of the gallbladder. The variance and regression analyses of the biochemical data have shown that alcohol significantly and considerably increases the activities of all three enzymes tested. For the second group, the reward presentation was accompanied by light and sound stimuli. There were no significant differences between treated and control females with respect to fertility indices, average number of implants/pregnant female, average number of dead implants/pregnant female, and proportions of female with one or more dead implants.[Litton Bionetics, Inc.; Mutagenicity Evaluation of Toluene, Mouse Dominant Lethal Assay, Final Report. Five rats/group in the acute study were sacrificed 6, 24 or 48 hrs following dosing and the rats in the subchronic study were sacrificed 6 hrs after administration of the last dose. [Environment Canada; Tech Info for Problem Spills: Toluene (Draft) p.3 (1979)]**PEER REVIEWED** Explosive Limits & Potential: LEL: 1.27%; UEL: 7%.